BLADE RUNNER. The name alone is enough to fill me up with happiness for the existence of such a movie. Once someone asked me why that was my all time favorite movie? From the various answers I could give at that moment the most simple was "I watched that movie more than 50 times and I loved it every time!".
Now the very recent final cut of the movie was for me the very best, and I was happy to know that Ridley Scott was still very involved with this final making of is work and the documentary in the extras disc was actually the pearl in the box set I bought, and since I wasn't able to watch the actual movie in the cinemas when it came out I had the luck of watching this final cut in a big ass cinema screen for the first time and making me the happiest fan in the world.
Some people don't know, but in 1997 there was a point and click adventure game for the PC launched by WESTWOOD. The way they went with the story was instead of adapting it from the movie, they decided to create a storyline that in very few occasions cross paths with Deckard investigation.
In the game you are Ray MacCoy is a rookie Blade Runner given the task to investigate the murder of animals (a crime nearly as heinous as murdering humans, since most animal species are extinct, and real specimens are exceedingly rare) by a suspected group of REPLICANTS.
Depending on your decisions and questions made during the gameplay, you may end up in one of the five possible endings.
The replicates the ambient and tone of the movie almost to perfection with soundtrack bits taken from the original soundtrack and you get to visit some of the places that you see in the actual movie.
Now in my humble opinion as a fan of the movie, the best way to make a sequel of this movie is simply to go ANIME with it. Movies like the ANIMATRIX, BATMAN-GOTHAM KNIGHT or HIGHLANDER-The Search for vengeance .
The anime could go the same way in story as the game went. A parallel story to the original movie with a new Blade Runner hunting a new group of Replicants and maybe occasionally crossing paths with Deckard or other already known characters.
If I could pick the team to make such a film I would have pick the same one that adapted "Ghost in the Shell" . They would be perfect to translate into animation the Blade Runner world.